Madness

Madness is infection of the foremost cell of the head, with privation of imagination, like as melancholy is the infection of the middle cell of the head, with privation of reason.

Madness cometh sometime of passions of the soul, as of business and of great thoughts, of sorrow and of too great study, and of dread: sometime of the biting of a wood hound, or some other venomous beast: sometime of melancholy meats, and sometime of drink of strong wine. And as the causes be diverse, the tokens and signs be diverse. For some cry and leap and hurt and wound themselves and other men, and darken and hide themselves in privy and secret places. The medicine of them is, that they be bound, that they hurt not themselves and other men. And namely, such shall be refreshed, and comforted, and withdrawn from cause and matter of dread and busy thoughts. And they must be gladded with instruments of music, and somedeal be occupied.

Source: Mediaeval Lore from Bartholomew Anglicus, Robert Steele